!!This displayer contains script commands. You should enable JavaScripting within your browser preferences, or use another browser!
USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
Search by
Maps
Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository
Exclude local DBs
has only effect if a remote
interface is selected
Searching in 'USC-OGP 2-DE database' for entry
matching:
PGAM1_HUMAN
USC-OGP 2-DE database
:
PGAM1_HUMAN
PGAM1_HUMAN
General information about the entry
View entry in simple text format
Entry name
PGAM1_HUMAN
Primary accession number
P18669
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Phosphoglycerate mutase 1; EC=5.4.2.11 {ECO:0000269|PubMed:23653202}; EC=5.4.2.4 {ECO:0000269|PubMed:23653202}; AltName: Full=BPG-dependent PGAM 1; AltName: Full=Phosphoglycerate mutase isozyme B; Short=PGAM-B;.
Gene name
Name=PGAM1
Synonyms=PGAMA
ORFNames=CDABP0006
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0506
:
pI=6.74; Mw=27760
PLATELET_6-11
{PLATELET 6-11}
Homo sapiens (Human)
map experimental info
PLATELET_6-11
MAP LOCATIONS:
SPOT OGP-1008
:
pI=6.69; Mw=27158
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1277
:
pI=6.93; Mw=27368
SPOT OGP-1278
:
pI=5.09; Mw=26938
Cross-references
UniProtKB/Swiss-Prot
P18669; PGAM1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PGAM1_HUMAN
Primary accession number
P18669
Secondary accession number(s)
Q9BWC0
Sequence was last modified on
January 23, 2007 (version 2)
Annotations were last modified on
March 15, 2017 (version 201)
Name and origin of the protein
Description
RecName: Full=Phosphoglycerate mutase 1; EC=5.4.2.11 {ECO:0000269|PubMed:23653202}; EC=5.4.2.4 {ECO:0000269|PubMed:23653202}; AltName: Full=BPG-dependent PGAM 1; AltName: Full=Phosphoglycerate mutase isozyme B; Short=PGAM-B;
Gene name
Name=PGAM1
Synonyms=PGAMA
ORFNames=CDABP0006
Encoded on
Name=PGAM1; Synonyms=PGAMA; ORFNames=CDABP0006
Keywords
3D-structure
;
Acetylation
;
Complete proteome
;
Direct protein sequencing
;
Glycolysis
;
Hydrolase
;
Isomerase
;
Phosphoprotein
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
J04173; AAA60071.1
; -; mRNA
EMBL
AY007118; AAG01990.1
; -; mRNA
EMBL
BC010038; AAH10038.1
; -; mRNA
EMBL
BC011678; AAH11678.1
; -; mRNA
EMBL
BC053356; AAH53356.1
; -; mRNA
EMBL
BC066959; AAH66959.1
; -; mRNA
EMBL
BC073742; AAH73742.1
; -; mRNA
CCDS
CCDS7458.1; -
; .
PIR
A31782; PMHUYB
; .
RefSeq
NP_002620.1; NM_002629.3
; .
UniGene
Hs.632918; -
; .
PDB
1LJD; Model
; -; A=1-254
PDB
1YFK; X-ray
; 2.70 A; A/B=1-254
PDB
1YJX; X-ray
; 2.80 A; A/B/C/D/E/F/G/H/I/J/K/L=1-254
PDB
4GPI; X-ray
; 2.08 A; B/C=1-254
PDB
4GPZ; X-ray
; 1.65 A; A/B=1-254
PDBsum
1LJD; -
; .
PDBsum
1YFK; -
; .
PDBsum
1YJX; -
; .
PDBsum
4GPI; -
; .
PDBsum
4GPZ; -
; .
ProteinModelPortal
P18669; -
; .
SMR
P18669; -
; .
BioGrid
111244; 39
; .
IntAct
P18669; 14
; .
MINT
MINT-3008987; -
; .
STRING
9606.ENSP00000359991; -
; .
ChEMBL
CHEMBL3334418; -
; .
DEPOD
P18669; -
; .
iPTMnet
P18669; -
; .
PhosphoSitePlus
P18669; -
; .
SwissPalm
P18669; -
; .
BioMuta
PGAM1; -
; .
DMDM
130348; -
; .
DOSAC-COBS-2DPAGE
P18669; -
; .
OGP
P18669; -
; .
SWISS-2DPAGE
P18669; -
; .
UCD-2DPAGE
P18669; -
; .
EPD
P18669; -
; .
PaxDb
P18669; -
; .
PeptideAtlas
P18669; -
; .
PRIDE
P18669; -
; .
TopDownProteomics
P18669; -
; .
DNASU
5223; -
; .
Ensembl
ENST00000334828; ENSP00000359991
; ENSG00000171314; .
GeneID
5223; -
; .
KEGG
hsa:5223; -
; .
CTD
5223; -
; .
DisGeNET
5223; -
; .
GeneCards
PGAM1; -
; .
H-InvDB
HIX0036336; -
; .
H-InvDB
HIX0120028; -
; .
HGNC
HGNC:8888; PGAM1
; .
HPA
HPA042528; -
; .
HPA
HPA049237; -
; .
HPA
HPA060483; -
; .
MIM
172250; gene
; .
neXtProt
NX_P18669; -
; .
OpenTargets
ENSG00000171314; -
; .
PharmGKB
PA33225; -
; .
eggNOG
KOG0235; Eukaryota
; .
eggNOG
COG0588; LUCA
; .
GeneTree
ENSGT00390000016700; -
; .
HOGENOM
HOG000221682; -
; .
HOVERGEN
HBG027528; -
; .
InParanoid
P18669; -
; .
KO
K01834; -
; .
OMA
VKNQGKK; -
; .
OrthoDB
EOG091G0GIS; -
; .
PhylomeDB
P18669; -
; .
TreeFam
TF300007; -
; .
BioCyc
MetaCyc:HS10286-MONOMER; -
; .
BRENDA
5.4.2.11; 2681
; .
Reactome
R-HSA-6798695; Neutrophil degranulation
; .
Reactome
R-HSA-70171; Glycolysis
; .
Reactome
R-HSA-70263; Gluconeogenesis
; .
SABIO-RK
P18669; -
; .
SIGNOR
P18669; -
; .
ChiTaRS
PGAM1; human
; .
EvolutionaryTrace
P18669; -
; .
GenomeRNAi
5223; -
; .
PRO
PR:P18669; -
; .
Proteomes
UP000005640; Chromosome 10
; .
Bgee
ENSG00000171314; -
; .
CleanEx
HS_PGAM1; -
; .
ExpressionAtlas
P18669; baseline and differential
; .
Genevisible
P18669; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:UniProtKB; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005576; C:extracellular region
; TAS:Reactome; .
GO
GO:1904813; C:ficolin-1-rich granule lumen
; TAS:Reactome; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0043209; C:myelin sheath
; IEA:Ensembl; .
GO
GO:0034774; C:secretory granule lumen
; TAS:Reactome; .
GO
GO:0046538; F:2
; 3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; IBA:GO_Central
GO
GO:0004082; F:bisphosphoglycerate mutase activity
; IEA:UniProtKB-EC; .
GO
GO:0016787; F:hydrolase activity
; IEA:UniProtKB-KW; .
GO
GO:0004619; F:phosphoglycerate mutase activity
; IDA:UniProtKB; .
GO
GO:0019901; F:protein kinase binding
; IPI:UniProtKB; .
GO
GO:0061621; P:canonical glycolysis
; TAS:Reactome; .
GO
GO:0006094; P:gluconeogenesis
; IBA:GO_Central; .
GO
GO:0006096; P:glycolytic process
; IDA:UniProtKB; .
GO
GO:0043312; P:neutrophil degranulation
; TAS:Reactome; .
GO
GO:0006110; P:regulation of glycolytic process
; IDA:UniProtKB; .
GO
GO:0043456; P:regulation of pentose-phosphate shunt
; IDA:UniProtKB; .
GO
GO:0045730; P:respiratory burst
; IDA:UniProtKB; .
CDD
cd07067; HP_PGM_like
; 1; .
Gene3D
3.40.50.1240; -
; 1; .
HAMAP
MF_01039; PGAM_GpmA
; 1; .
InterPro
IPR013078; His_Pase_superF_clade-1
; .
InterPro
IPR029033; His_PPase_superfam
; .
InterPro
IPR001345; PG/BPGM_mutase_AS
; .
InterPro
IPR005952; Phosphogly_mut1
; .
PANTHER
PTHR11931; PTHR11931
; 1; .
Pfam
PF00300; His_Phos_1
; 2; .
SMART
SM00855; PGAM
; 1; .
SUPFAM
SSF53254; SSF53254
; 1; .
TIGRFAMs
TIGR01258; pgm_1
; 1; .
PROSITE
PS00175; PG_MUTASE
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
[
Home
]